Dr. Frank Lipman of Eleven Eleven Wellness Center in New York City was clear about the importance of foundational habits for increased longevity during the 2025 ATN CEO Summit.
“You can’t get away from the basics,” said Lipman. “You can try all the peptides, supplements, and tech in the world, but if you’re not sleeping well, eating right, and managing stress, it’s not going to help you live a healthier, longer life.” You could take all the supplements in the world, but if you’re eating poorly and not sleeping, you’re not going to age well.”
Lipman shared his journey with brain health, driven by his genetic predisposition to Alzheimer’s. “I’m obsessed with brain optimization,” he admitted. “It’s not just about preventing cognitive decline; it’s about keeping your mind sharp and focused as you age.”
He highlighted the role of mitochondrial function in cognitive health. “Cognitive decline is tied to mitochondrial dysfunction,” Lipman explained. “Optimizing your mitochondria—through temperature extremes, exercise, and targeted supplements—can make a huge difference.”
Among his go-to strategies were ketones, nootropics, and supplements like methylene blue. “Every morning, I start with black coffee and ketones,” he said. “It’s a simple routine, but it’s incredibly effective for brain health.”
It’s no secret that stress undermines health. “We live in an age of overstimulation and low-grade anxiety,” Dr. Lipman noted. While meditation remains a gold standard, he acknowledged that it’s not feasible for everyone.
“There are other tools available now,” he said, listing vagus nerve stimulators, magnesium, and newer supplements like THP from magnolia leaf. “You don’t have to spend $10,000 on a chair like Shiftwave that sends pressure waves through your body to relax—although it works. There are simpler options like vagus nerve stimulators, which cost a few hundred dollars.”
The Dangers of Chronic Stress
Lipman also emphasized the importance of addressing stress for longevity: “Low-grade stress affects our DNA and accelerates aging. This is an area most people overlook, but it’s crucial to manage for overall health.”
When asked about high-tech interventions, Lipman offered a wish list that included a hyperbaric oxygen chamber, a sauna and a cold plunge. He also expressed enthusiasm for GLP-1 receptor agonists, commonly used for weight loss but increasingly explored for their longevity benefits.
“I use low-dose GLP-1s not for weight loss, but for anti-aging,” he said. “They’re neuroprotective, cardioprotective, and anti-inflammatory. When used responsibly, they’re magical.”
Lipman also addressed the disparities in women’s healthcare, particularly during perimenopause and menopause. “Women get shafted in medicine,” he said bluntly. “Hormone optimization is critical, but it’s often ignored or dismissed by doctors.”
He advocated for responsible hormone replacement therapy, starting with progesterone and testosterone. “Testosterone isn’t just a male hormone. Women love their testosterone, and it makes a huge difference in quality of life.”
At the end of the session, Lipman cautioned against the proliferation of unproven health products. “There’s a lot of snake oil out there,” he warned, citing IV NAD as an example. “It’s expensive, and the benefits are short-lived. Focus on interventions with proven, lasting effects.”
Be on the lookout for more information on the ATN Innovation Summit, a can’t-miss two-day event to be held on June 17th and 18th in New York City featuring the biggest names, brands, and ideas across fitness, health, and wellness.
